Source: BIOENGINEERING-BASEL Volume: 10  Issue: 5  Article Number: 578  DOI: 10.3390/bioengineering10050578  Published: MAY 10 2023 

 

Abstract: Neural electrodes are core devices for research in neuroscience, neurological diseases, and neural-machine interfacing. They build a bridge between the cerebral nervous system and electronic devices. Most of the neural electrodes in use are based on rigid materials that differ significantly from biological neural tissue in flexibility and tensile properties. In this study, a liquid-metal (LM) -based 20-channel neural electrode array with a platinum metal (Pt) encapsulation material was developed by microfabrication technology. The in vitro experiments demonstrated that the electrode has stable electrical properties and excellent mechanical properties such as flexibility and bending, which allows the electrode to form conformal contact with the skull. The in vivo experiments also

 

Recorded electroencephalographic signals using the LM-based electrode from a rat under low-flow or deep anesthesia, including the auditory-evoked potentials triggered by sound stimulation. The auditory-activated cortical area was analyzed using source localization technique. These results indicate that this 20-channel LM-based neural electrode array satisfies the demands of brain signal acquisition and provides high-quality-electroencephalogram (EEG) signals that support source localization analysis.

 

Accession Number: WOS:000995610700001

 

PubMed ID: 37237648

 

Author Identifiers:

 

Author Web of Science ResearcherID ORCID Number

 

Gui, Lin          0000-0002-8015-0791

 

eISSN: 2306-5354